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pentobarbital will reduce the level or influence of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with potent CYP3A4 inducers just isn't advisableDon't use pentobarbital in individuals with hypersensitivity to barbiturates or any in the elements in pentobarbital.Pentobarbital interacts